Mary MacKillop Institute for Health Research

Participants needed for metabolic study


How does exercise influence the metabolic systems that control the body’s natural circadian rhythm?

The body’s natural circadian clock is regulated by night and day cycles, temperature, dietary intake and physical intake. Disruptions to the daily patterns of meal consumption and timing are associated with the development of metabolic diseases. The influence of exercise on the circadian clock in humans is currently unknown. This project will determine the effects of a high fat diet with and without exercise on the normal circadian rhythm.

What is involved?

  • Attending the laboratory on a maximum of 11 occasions involving blood sampling, muscle biopsies, measurements of body composition, diet, physical fitness and physical activity.
  • Consuming a provided study diet for a 11 day period (high fat). The timing of food intake will be controlled and each day breakfast, lunch and dinner will be provided.
  • Randomised to a condition where you either attend the laboratory to exercise for five days (either in the morning or the evening) or do not exercise (control).

Benefits to participation

•  Metabolic health profile in the form of an individual report at the conclusion of this study
•  Advancing medical research
•  Nine days of food provided at no personal cost
•  Compensation for your time in the study
•  Supervised training for five days (participants allocated to the control group will receive supervised training after the study completion if they want)

Who can participate?

Eligible participants will be male, aged between 30 to 45 years, currently be sedentary and have a BMI between 27 and 35 kg/m2.

PDF PicParticipant Information Letter


For more information please contact:

Dr Trine Moholdt
Study Coordinator
0429 111 151

Miss Bridget Radford
Research Assistant
03 9230 8284 or 0431 474 121

Ethics approval: 2016-254H






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